Proteins/UNIPROT:Q9NP62

GCM1

ProteinUNIPROT:Q9NP62

Transcription factor involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development..

Function from UniProtKB (Q9NP62), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

19 statements

19 statements · 2 reference databases · Subject: GCM1 · Sources: gene ontology, Hetionet

Order

GCM1 covaries with ZIC1ProteinHetionet hetionet:covaries:7545-8521Inferred only
GCM1 interacts with CAMK1ProteinHetionet hetionet:interacts:8521-8536Inferred only
CREBBP interacts with GCM1ProteinHetionet hetionet:interacts:1387-8521Inferred only
CUL1 interacts with GCM1ProteinHetionet hetionet:interacts:8454-8521Inferred only
GCM1 interacts with DUSP23ProteinHetionet hetionet:interacts:54935-8521Inferred only
GCM1 interacts with FBXW2ProteinHetionet hetionet:interacts:26190-8521Inferred only
HDAC1 interacts with GCM1ProteinHetionet hetionet:interacts:3065-8521Inferred only
GCM1 interacts with HDAC3ProteinHetionet hetionet:interacts:8521-8841Inferred only
GCM1 interacts with HDAC4ProteinHetionet hetionet:interacts:8521-9759Inferred only
GCM1 interacts with HDAC5ProteinHetionet hetionet:interacts:10014-8521Inferred only
SUMO1 interacts with GCM1ProteinHetionet hetionet:interacts:7341-8521Inferred only
UBC interacts with GCM1ProteinHetionet hetionet:interacts:7316-8521Inferred only

Show the remaining 7

UBE2I interacts with GCM1ProteinHetionet hetionet:interacts:7329-8521Inferred only
GCM1 regulates positive regulation of DNA-templated transcriptionBiological processgene ontology Q9NP62|GO:0045893Inferred only
GCM1 regulates positive regulation of transcription by RNA polymerase IIBiological processgene ontology Q9NP62|GO:0045944Inferred only
GCM1 regulates regulation of cell differentiation involved in embryonic placenta developmentBiological processgene ontology Q9NP62|GO:0060800Inferred only
GCM1 regulates regulation of DNA-templated transcriptionBiological processgene ontology Q9NP62|GO:0006355Inferred only
GCM1 regulates regulation of transcription by RNA polymerase IIBiological processgene ontology Q9NP62|GO:0006357Inferred only
GCM1 increases the expression of PHKG2ProteinHetionet hetionet:regulates:8521-5261Inferred only

Other names

4 names

Resolves to: GCM1

Also called: GCM motif protein 1GCMAGlial cells missing homolog 1hGCMa

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