Proteins/UNIPROT:Q969F0

FATE1

ProteinUNIPROT:Q969F0

Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling..

Function from UniProtKB (Q969F0), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

13 statements

13 statements · 2 reference databases · Subject: FATE1 · Sources: gene ontology, Hetionet

Order

BIK interacts with FATE1ProteinHetionet hetionet:interacts:638-89885Inferred only
EMD interacts with FATE1ProteinHetionet hetionet:interacts:2010-89885Inferred only
FATE1 interacts with NRG4ProteinHetionet hetionet:interacts:145957-89885Inferred only
FATE1 interacts with RNF183ProteinHetionet hetionet:interacts:138065-89885Inferred only
FATE1 interacts with SMIM14ProteinHetionet hetionet:interacts:201895-89885Inferred only
SYNGR2 interacts with FATE1ProteinHetionet hetionet:interacts:89885-9144Inferred only
TBP interacts with FATE1ProteinHetionet hetionet:interacts:6908-89885Inferred only
TMEM11 interacts with FATE1ProteinHetionet hetionet:interacts:8834-89885Inferred only
TRAF2 interacts with FATE1ProteinHetionet hetionet:interacts:7186-89885Inferred only
USHBP1 interacts with FATE1ProteinHetionet hetionet:interacts:83878-89885Inferred only
YIPF2 interacts with FATE1ProteinHetionet hetionet:interacts:78992-89885Inferred only
FATE1 regulates negative regulation of apoptotic processBiological processgene ontology Q969F0|GO:0043066Inferred only

Show the remaining 1

FATE1 regulates negative regulation of mitochondrial calcium ion concentrationBiological processgene ontology Q969F0|GO:0051562Inferred only

Other names

4 names

Resolves to: FATE1

Also called: Cancer/testis antigen 43CT43FATETumor antigen BJ-HCC-2

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