Proteins/UNIPROT:Q9HCE0

EPG5

ProteinUNIPROT:Q9HCE0

Involved in autophagy. May play a role in a late step of autophagy, such as clearance of autophagosomal cargo. Plays a key role in innate and adaptive immune response triggered by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides from pathogens, and mediated by the nucleotide-sensing receptor TLR9. It is necessary for the translocation of CpG dinucleotides from early endosomes to late endosomes and lysosomes, where TLR9 is located..

Function from UniProtKB (Q9HCE0), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

Vici syndrome has a germline basis in EPG5DiseaseGenCC HGNC:29331|MONDO:0009452Inferred only

Statements

9 statements

9 statements · 1 reference database · Subject: EPG5 · Sources: Hetionet

Order

CDK3 covaries with EPG5ProteinHetionet hetionet:covaries:1018-57724Inferred only
FBN3 covaries with EPG5ProteinHetionet hetionet:covaries:57724-84467Inferred only
NEK3 covaries with EPG5ProteinHetionet hetionet:covaries:4752-57724Inferred only
EPG5 covaries with RDM1ProteinHetionet hetionet:covaries:201299-57724Inferred only
VPS13B covaries with EPG5ProteinHetionet hetionet:covaries:157680-57724Inferred only
ZNF581 covaries with EPG5ProteinHetionet hetionet:covaries:51545-57724Inferred only
ZNF699 covaries with EPG5ProteinHetionet hetionet:covaries:374879-57724Inferred only
ATF7IP interacts with EPG5ProteinHetionet hetionet:interacts:55729-57724Inferred only
UBC interacts with EPG5ProteinHetionet hetionet:interacts:57724-7316Inferred only

Other names

2 names

Resolves to: EPG5

Also called: Ectopic P granules protein 5 homologKIAA1632

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