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Proteins/UNIPROT:Q9Y6X5
Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors..
Function from UniProtKB (Q9Y6X5), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
21 statements
21 statements · 6 reference databases · Subject: ENPP4 · Sources: Bgee, gene ontology, Hetionet, Reactome, Rhea, UniProt
1 reaction
P(1),P(3)-bis(5'-adenosyl) triphosphate+waterAMP+ADP(3-)+2hydron
Catalysed by ENPP3 or FHIT or ENPP4
Reaction pageLeft to rightBalanced
Rhea RHEA:13893CC BY 4.0Reference data
8 names
Resolves to: ENPP4