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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:Q92874

DNASE1L2

Protein·UNIPROT:Q92874

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Divalent cation-dependent acid DNA endonuclease involved in the breakdown of the nucleus during corneocyte formation of epidermal keratinocytes. May play an immune role by eliminating harmful DNA released into the extracellular environment by damaged epidermal cells..

Function from UniProtKB (Q92874), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

4 statements

4 statements · 2 reference databases · Subject: DNASE1L2 · Sources: Hetionet, UniProt

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ABL1 interacts with DNASE1L2ProteinHetionet hetionet:interacts:1775-25Inferred only
DNASE1L2 interacts with FYNProteinHetionet hetionet:interacts:1775-2534Inferred only
DNASE1L2 requires the cofactor Ca(2+)CompoundUniProt Q92874Inferred only
DNASE1L2 requires the cofactor magnesium(2+)CompoundUniProt Q92874Inferred only

Other names

5 names

Resolves to: DNASE1L2

Also called: Deoxyribonuclease I-like 2DHP1DNAS1L2DNase I homolog protein DHP1DNase I-like 2

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