Proteins/UNIPROT:Q92904

DAZL

ProteinUNIPROT:Q92904

RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity)..

Function from UniProtKB (Q92904), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

primary ovarian failure has a germline basis in DAZLDiseaseGenCC HGNC:2685|MONDO:0005387Inferred only

Statements

13 statements

13 statements · 3 reference databases · Subject: DAZL · Sources: gene ontology, Hetionet, WikiPathways

Order

CNGA2 covaries with DAZLProteinHetionet hetionet:covaries:1260-1618Inferred only
DAZL covaries with DMRTC2ProteinHetionet hetionet:covaries:1618-63946Inferred only
TKTL1 covaries with DAZLProteinHetionet hetionet:covaries:1618-8277Inferred only
DAZ1 interacts with DAZLProteinHetionet hetionet:interacts:1617-1618Inferred only
DAZL interacts with DAZ4ProteinHetionet hetionet:interacts:1618-57135Inferred only
DAZL interacts with DAZAP1ProteinHetionet hetionet:interacts:1618-26528Inferred only
DAZL interacts with DAZAP2ProteinHetionet hetionet:interacts:1618-9802Inferred only
DAZL interacts with PUM2ProteinHetionet hetionet:interacts:1618-23369Inferred only
DAZL interacts with UBCProteinHetionet hetionet:interacts:1618-7316Inferred only
DAZL participates in Male infertilityPathwayWikiPathways WP4673Inferred only
DAZL participates in Ovarian infertilityPathwayWikiPathways WP34Inferred only
DAZL participates in Primary ovarian insufficiencyPathwayWikiPathways WP5461Inferred only

Show the remaining 1

DAZL regulates positive regulation of translational initiationBiological processgene ontology Q92904|GO:0045948Inferred only

Other names

8 names

Resolves to: DAZL

Also called: DAZ homologDAZ-like autosomalDAZHDAZL1DAZLADeleted in azoospermia-like 1SPGY-like-autosomalSPGYLA

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