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Proteins/UNIPROT:Q8N0S6

CENPL

Protein·UNIPROT:Q8N0S6

Open in the graph

Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex..

Function from UniProtKB (Q8N0S6), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

23 statements

23 statements · 2 reference databases · Subject: CENPL · Sources: Hetionet, Reactome

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NLRC4 covaries with CENPLProteinHetionet hetionet:covaries:58484-91687Inferred only
OCM2 covaries with CENPLProteinHetionet hetionet:covaries:4951-91687Inferred only
CENPL participates in Amplification of signal from unattached kinetochores via a MAD2 inhibitory signalPathwayReactome R-HSA-141444Inferred only
CENPL participates in Amplification of signal from the kinetochoresPathwayReactome R-HSA-141424Inferred only
CENPL participates in Cell CyclePathwayReactome R-HSA-1640170Inferred only
CENPL participates in Cell Cycle CheckpointsPathwayReactome R-HSA-69620Inferred only
CENPL participates in Cell Cycle, MitoticPathwayReactome R-HSA-69278Inferred only
CENPL participates in Chromosome MaintenancePathwayReactome R-HSA-73886Inferred only
CENPL participates in Deposition of new CENPA-containing nucleosomes at the centromerePathwayReactome R-HSA-606279Inferred only
CENPL participates in EML4 and NUDC in mitotic spindle formationPathwayReactome R-HSA-9648025Inferred only
CENPL participates in M PhasePathwayReactome R-HSA-68886Inferred only
CENPL participates in Mitotic AnaphasePathwayReactome R-HSA-68882Inferred only

Show the remaining 11

CENPL participates in Mitotic Metaphase and AnaphasePathwayReactome R-HSA-2555396Inferred only
CENPL participates in Mitotic PrometaphasePathwayReactome R-HSA-68877Inferred only
CENPL participates in Mitotic Spindle CheckpointPathwayReactome R-HSA-69618Inferred only
CENPL participates in Nucleosome assemblyPathwayReactome R-HSA-774815Inferred only
CENPL participates in Resolution of Sister Chromatid CohesionPathwayReactome R-HSA-2500257Inferred only
CENPL participates in RHO GTPase EffectorsPathwayReactome R-HSA-195258Inferred only
CENPL participates in RHO GTPases Activate ForminsPathwayReactome R-HSA-5663220Inferred only
CENPL participates in Separation of Sister ChromatidsPathwayReactome R-HSA-2467813Inferred only
CENPL participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
CENPL participates in Signaling by Rho GTPasesPathwayReactome R-HSA-194315Inferred only
CENPL participates in Signaling by Rho GTPases, Miro GTPases and RHOBTB3PathwayReactome R-HSA-9716542Inferred only

Other names

4 names

Resolves to: CENPL

Also called: C1orf155CENP-LICEN33Interphase centromere complex protein 33

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