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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:Q8N7E2

CBLL2

Protein·UNIPROT:Q8N7E2

Open in the graph

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. May operate on tyrosine-phosphorylated SRC substrates..

Function from UniProtKB (Q8N7E2), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

6 statements

6 statements · 3 reference databases · Subject: CBLL2 · Sources: gene ontology, Hetionet, Reactome

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UBC interacts with CBLL2ProteinHetionet hetionet:interacts:158506-7316Inferred only
CBLL2 participates in Adaptive Immune SystemPathwayReactome R-HSA-1280218Inferred only
CBLL2 participates in Antigen processing: Ubiquitination & Proteasome degradationPathwayReactome R-HSA-983168Inferred only
CBLL2 participates in Class I MHC mediated antigen processing & presentationPathwayReactome R-HSA-983169Inferred only
CBLL2 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
CBLL2 regulates regulation of cell adhesionBiological processgene ontology Q8N7E2|GO:0030155Inferred only

Reactions

1 reaction

MAM00204c+ATP+MAM03105cMAM00214c+AMP+diphosphate(3-)
Catalysed by RNF40 & RNF20 or SAE1 & UBA2 or RING1 & RNF2 or HECW1 or MYCBP2 or MYLIP or UBE3C or RNF216 or UBR7 or RNF14 or UBR2

Other names

5 names

Resolves to: CBLL2

Also called: c-Cbl-like protein 2Cbl proto-oncogene-like protein 2RING-type E3 ubiquitin transferase ZNF645Zinc finger protein 645ZNF645

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or UBA6

and 160 more alternatives

Reaction pageLeft to rightBalance undeterminableEC 2.3.2.23, 2.3.2.27, 6.2.1.45cytosol

Human-GEM MAR09491CC BY 4.0Reference data