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Proteins/UNIPROT:Q86XQ3

CATSPER3

Protein·UNIPROT:Q86XQ3

Open in the graph

Pore-forming subunit of the CatSper complex, a sperm-specific voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte..

Function from UniProtKB (Q86XQ3), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

5 statements

5 statements · 3 reference databases · Subject: CATSPER3 · Sources: Hetionet, Reactome, Rhea

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SLC25A41 covaries with CATSPER3ProteinHetionet hetionet:covaries:284427-347732Inferred only
CATSPER3 participates in FertilizationPathwayReactome R-HSA-1187000Inferred only
CATSPER3 participates in ReproductionPathwayReactome R-HSA-1474165Inferred only
CATSPER3 participates in Sperm Motility And TaxesPathwayReactome R-HSA-1300642Inferred only
Ca(2+) is transported by CATSPER3CompoundRhea RHEA:29671Inferred only

Reactions

1 reaction

Ca(2+)Ca(2+)
Transported by ANO9 or HTR3E or TMEM150C or CACNA1A or GRIN2D or P2RX6 or GRID2 or CACNA1G or GRIN3B or CACNA1F or TRPA1 or TRPM2 and 106 more alternatives
Reaction pageRight to leftBalanced
Rhea RHEA:29671CC BY 4.0Reference data

Other names

2 names

Resolves to: CATSPER3

Also called: Ca(v)-like proteinOne-repeat calcium channel-like protein

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