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Proteins/UNIPROT:Q96P56

CATSPER2

Protein·UNIPROT:Q96P56

Open in the graph

Pore-forming subunit of the CatSper complex, a sperm-specific voltage-gated calcium channel, that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte..

Function from UniProtKB (Q96P56), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

7 statements

7 statements · 3 reference databases · Subject: CATSPER2 · Sources: Hetionet, Reactome, Rhea

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BCL2 covaries with CATSPER2ProteinHetionet hetionet:covaries:117155-596Inferred only
TSNAXIP1 covaries with CATSPER2ProteinHetionet hetionet:covaries:117155-55815Inferred only
CACNA1I interacts with CATSPER2ProteinHetionet hetionet:interacts:117155-8911Inferred only
CATSPER2 participates in FertilizationPathwayReactome R-HSA-1187000Inferred only
CATSPER2 participates in ReproductionPathwayReactome R-HSA-1474165Inferred only
CATSPER2 participates in Sperm Motility And TaxesPathwayReactome R-HSA-1300642Inferred only
Ca(2+) is transported by CATSPER2CompoundRhea RHEA:29671Inferred only

Reactions

1 reaction

Ca(2+)Ca(2+)
Transported by ANO9 or HTR3E or TMEM150C or CACNA1A or GRIN2D or P2RX6 or GRID2 or CACNA1G or GRIN3B or CACNA1F or TRPA1 or TRPM2 and 106 more alternatives
Reaction pageRight to leftBalanced
Rhea RHEA:29671CC BY 4.0Reference data

Other names

1 name

Resolves to: CATSPER2

Also called: Cation channel sperm-associated protein 2

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