Proteins/UNIPROT:Q02641

CACNB1

ProteinUNIPROT:Q02641

Regulatory subunit of L-type calcium channels. Regulates the activity of L-type calcium channels that contain CACNA1A as pore-forming subunit (By similarity). Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit and increases the presence of the channel complex at the cell membrane. Required for functional expression L-type calcium channels that contain CACNA1D as pore-forming subunit. Regulates the activity of L-type calcium channels that contain CACNA1B as pore-forming subunit..

Function from UniProtKB (Q02641), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

39 statements

39 statements · 4 reference databases · Subject: CACNB1 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

BRI3 covaries with CACNB1ProteinHetionet hetionet:covaries:25798-782Inferred only
BTBD19 covaries with CACNB1ProteinHetionet hetionet:covaries:149478-782Inferred only
CACNB1 covaries with C17orf50ProteinHetionet hetionet:covaries:146853-782Inferred only
FZD9 covaries with CACNB1ProteinHetionet hetionet:covaries:782-8326Inferred only
GPR173 covaries with CACNB1ProteinHetionet hetionet:covaries:54328-782Inferred only
ISYNA1 covaries with CACNB1ProteinHetionet hetionet:covaries:51477-782Inferred only
PLOD3 covaries with CACNB1ProteinHetionet hetionet:covaries:782-8985Inferred only
CACNB1 covaries with RLBP1ProteinHetionet hetionet:covaries:6017-782Inferred only
APP interacts with CACNB1ProteinHetionet hetionet:interacts:351-782Inferred only
CACNB1 interacts with ATN1ProteinHetionet hetionet:interacts:1822-782Inferred only
CACNA1A interacts with CACNB1ProteinHetionet hetionet:interacts:773-782Inferred only
CACNA1C interacts with CACNB1ProteinHetionet hetionet:interacts:775-782Inferred only

Show the remaining 27

CACNB1 interacts with DYNLL1ProteinHetionet hetionet:interacts:782-8655Inferred only
CACNB1 interacts with GEMProteinHetionet hetionet:interacts:2669-782Inferred only
CACNB1 interacts with NEDD4LProteinHetionet hetionet:interacts:23327-782Inferred only
CACNB1 interacts with REM1ProteinHetionet hetionet:interacts:28954-782Inferred only
CACNB1 interacts with UBCProteinHetionet hetionet:interacts:7316-782Inferred only
CACNB1 participates in 17q12 copy number variation syndromePathwayWikiPathways WP5287Inferred only
CACNB1 participates in Affected pathways in Duchenne muscular dystrophyPathwayWikiPathways WP5356Inferred only
CACNB1 participates in Arrhythmogenic right ventricular cardiomyopathyPathwayWikiPathways WP2118Inferred only
CACNB1 participates in Axon guidancePathwayReactome R-HSA-422475Inferred only
CACNB1 participates in Calcium regulation in cardiac cellsPathwayWikiPathways WP536Inferred only
CACNB1 participates in Cardiac conductionPathwayReactome R-HSA-5576891Inferred only
CACNB1 participates in Cellular responses to mechanical stimuliPathwayReactome R-HSA-9855142Inferred only
CACNB1 participates in Cellular responses to stimuliPathwayReactome R-HSA-8953897Inferred only
CACNB1 participates in Developmental BiologyPathwayReactome R-HSA-1266738Inferred only
CACNB1 participates in MAPK signalingPathwayWikiPathways WP382Inferred only
CACNB1 participates in Mechanical load activates signaling by PIEZO1 and integrins in osteocytesPathwayReactome R-HSA-9856532Inferred only
CACNB1 participates in Muscle contractionPathwayReactome R-HSA-397014Inferred only
CACNB1 participates in NCAM signaling for neurite out-growthPathwayReactome R-HSA-375165Inferred only
CACNB1 participates in NCAM1 interactionsPathwayReactome R-HSA-419037Inferred only
CACNB1 participates in Nervous system developmentPathwayReactome R-HSA-9675108Inferred only
CACNB1 participates in Neuronal SystemPathwayReactome R-HSA-112316Inferred only
CACNB1 participates in Phase 0 - rapid depolarisationPathwayReactome R-HSA-5576892Inferred only
CACNB1 participates in Phase 2 - plateau phasePathwayReactome R-HSA-5576893Inferred only
CACNB1 participates in Presynaptic depolarization and calcium channel openingPathwayReactome R-HSA-112308Inferred only
CACNB1 participates in Transmission across Chemical SynapsesPathwayReactome R-HSA-112315Inferred only
CACNB1 regulates positive regulation of muscle contractionBiological processgene ontology Q02641|GO:0045933Inferred only
CACNB1 regulates regulation of calcium ion transmembrane transport via high voltage-gated calcium channelBiological processgene ontology Q02641|GO:1902514Inferred only

Other names

3 names

Resolves to: CACNB1

Also called: CAB1CACNLB1Calcium channel voltage-dependent subunit beta 1

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