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Proteins/UNIPROT:Q96PE2

ARHGEF17

Protein·UNIPROT:Q96PE2

Open in the graph

Acts as a guanine nucleotide exchange factor (GEF) for RhoA GTPases..

Function from UniProtKB (Q96PE2), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

16 statements

16 statements · 3 reference databases · Subject: ARHGEF17 · Sources: gene ontology, Hetionet, Reactome

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UBC interacts with ARHGEF17ProteinHetionet hetionet:interacts:7316-9828Inferred only
ARHGEF17 participates in Cell death signalling via NRAGE, NRIF and NADEPathwayReactome R-HSA-204998Inferred only
ARHGEF17 participates in Death Receptor SignalingPathwayReactome R-HSA-73887Inferred only
ARHGEF17 participates in G alpha (12/13) signalling eventsPathwayReactome R-HSA-416482Inferred only
ARHGEF17 participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
ARHGEF17 participates in NRAGE signals death through JNKPathwayReactome R-HSA-193648Inferred only
ARHGEF17 participates in p75 NTR receptor-mediated signallingPathwayReactome R-HSA-193704Inferred only
ARHGEF17 participates in RHO GTPase cyclePathwayReactome R-HSA-9012999Inferred only
ARHGEF17 participates in RHOA GTPase cyclePathwayReactome R-HSA-8980692Inferred only
ARHGEF17 participates in RHOB GTPase cyclePathwayReactome R-HSA-9013026Inferred only
ARHGEF17 participates in RHOC GTPase cyclePathwayReactome R-HSA-9013106Inferred only
ARHGEF17 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only

Show the remaining 4

ARHGEF17 participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only
ARHGEF17 participates in Signaling by Rho GTPasesPathwayReactome R-HSA-194315Inferred only
ARHGEF17 participates in Signaling by Rho GTPases, Miro GTPases and RHOBTB3PathwayReactome R-HSA-9716542Inferred only
ARHGEF17 regulates regulation of small GTPase mediated signal transductionBiological processgene ontology Q96PE2|GO:0051056Inferred only

Other names

6 names

Resolves to: ARHGEF17

Also called: 164 kDa Rho-specific guanine-nucleotide exchange factorKIAA0337p164-RhoGEFp164RhoGEFTEM4Tumor endothelial marker 4

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