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Proteins/UNIPROT:Q9Y235

APOBEC2

Protein·UNIPROT:Q9Y235

Open in the graph

Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation..

Function from UniProtKB (Q9Y235), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

7 statements

7 statements · 4 reference databases · Subject: APOBEC2 · Sources: gene ontology, Hetionet, Reactome, UniProt

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APOBEC1 interacts with APOBEC2ProteinHetionet hetionet:interacts:10930-339Inferred only
APOBEC2 participates in Formation of the EditosomePathwayReactome R-HSA-75094Inferred only
APOBEC2 participates in Metabolism of RNAPathwayReactome R-HSA-8953854Inferred only
APOBEC2 participates in mRNA EditingPathwayReactome R-HSA-75072Inferred only
APOBEC2 participates in mRNA Editing: C to U ConversionPathwayReactome R-HSA-72200Inferred only
APOBEC2 regulates positive regulation of gene expression via chromosomal CpG island demethylationBiological processgene ontology Q9Y235|GO:0044029Inferred only
APOBEC2 requires the cofactor Zn(2+)CompoundUniProt Q9Y235Inferred only

Reactions

1 reaction

CHEBI:82748+water+hydronCHEBI:65315+ammonium
Catalysed by APOBEC1 or APOBEC2
Reaction pageLeft to rightBalanced
Rhea RHEA:21772CC BY 4.0Reference data

Other names

1 name

Resolves to: APOBEC2

Also called: mRNA(cytosine(6666)) deaminase 2

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