Proteins/UNIPROT:Q86WK6

AMIGO1

ProteinUNIPROT:Q86WK6

Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1..

Function from UniProtKB (Q86WK6), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

11 statements

11 statements · 2 reference databases · Subject: AMIGO1 · Sources: gene ontology, Hetionet

Order

CCDC22 covaries with AMIGO1ProteinHetionet hetionet:covaries:28952-57463Inferred only
FCHSD1 covaries with AMIGO1ProteinHetionet hetionet:covaries:57463-89848Inferred only
MICOS13 covaries with AMIGO1ProteinHetionet hetionet:covaries:125988-57463Inferred only
NDN covaries with AMIGO1ProteinHetionet hetionet:covaries:4692-57463Inferred only
RNF112 covaries with AMIGO1ProteinHetionet hetionet:covaries:57463-7732Inferred only
AMIGO1 interacts with AMIGO2ProteinHetionet hetionet:interacts:347902-57463Inferred only
AMIGO1 interacts with AMIGO3ProteinHetionet hetionet:interacts:386724-57463Inferred only
AMIGO1 regulates positive regulation of axonogenesisBiological processgene ontology Q86WK6|GO:0050772Inferred only
AMIGO1 regulates positive regulation of neuron projection developmentBiological processgene ontology Q86WK6|GO:0010976Inferred only
AMIGO1 regulates positive regulation of potassium ion transmembrane transportBiological processgene ontology Q86WK6|GO:1901381Inferred only
AMIGO1 regulates positive regulation of synapse assemblyBiological processgene ontology Q86WK6|GO:0051965Inferred only

Other names

5 names

Resolves to: AMIGO1

Also called: ALI2Alivin-2AMIGOAMIGO-1KIAA1163

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