Proteins/UNIPROT:Q9H013

ADAM19

ProteinUNIPROT:Q9H013

Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity)..

Function from UniProtKB (Q9H013), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

29 statements

29 statements · 5 reference databases · Subject: ADAM19 · Sources: gene ontology, Hetionet, Reactome, UniProt, WikiPathways

Order

ADAM19 covaries with CERS1ProteinHetionet hetionet:covaries:10715-8728Inferred only
ADAM19 covaries with CLPXProteinHetionet hetionet:covaries:10845-8728Inferred only
ADAM19 covaries with FAM228AProteinHetionet hetionet:covaries:653140-8728Inferred only
PRR32 covaries with ADAM19ProteinHetionet hetionet:covaries:100130613-8728Inferred only
A2M interacts with ADAM19ProteinHetionet hetionet:interacts:2-8728Inferred only
ADAM19 interacts with ABI2ProteinHetionet hetionet:interacts:10152-8728Inferred only
COPB1 interacts with ADAM19ProteinHetionet hetionet:interacts:1315-8728Inferred only
FURIN interacts with ADAM19ProteinHetionet hetionet:interacts:5045-8728Inferred only
NRG1 interacts with ADAM19ProteinHetionet hetionet:interacts:3084-8728Inferred only
SH3GL2 interacts with ADAM19ProteinHetionet hetionet:interacts:6456-8728Inferred only
TNFSF11 interacts with ADAM19ProteinHetionet hetionet:interacts:8600-8728Inferred only
UBC interacts with ADAM19ProteinHetionet hetionet:interacts:7316-8728Inferred only

Show the remaining 17

ADAM19 participates in Adherens junctions interactionsPathwayReactome R-HSA-418990Inferred only
ADAM19 participates in Cell junction organizationPathwayReactome R-HSA-446728Inferred only
ADAM19 participates in Cell-Cell communicationPathwayReactome R-HSA-1500931Inferred only
ADAM19 participates in Cell-cell junction organizationPathwayReactome R-HSA-421270Inferred only
ADAM19 participates in Extracellular matrix organizationPathwayReactome R-HSA-1474244Inferred only
ADAM19 participates in Invadopodia formationPathwayReactome R-HSA-8941237Inferred only
ADAM19 participates in Mesodermal commitment pathwayPathwayWikiPathways WP2857Inferred only
ADAM19 participates in Regulation of CDH11 Expression and FunctionPathwayReactome R-HSA-9759475Inferred only
ADAM19 participates in Regulation of CDH11 functionPathwayReactome R-HSA-9762292Inferred only
ADAM19 participates in Regulation of Expression and Function of Type II Classical CadherinsPathwayReactome R-HSA-9764260Inferred only
ADAM19 participates in Regulation of Homotypic Cell-Cell AdhesionPathwayReactome R-HSA-9759476Inferred only
ADAM19 regulates positive regulation of cell-cell adhesion mediated by cadherinBiological processgene ontology Q9H013|GO:2000049Inferred only
ADAM19 regulates positive regulation of gene expressionBiological processgene ontology Q9H013|GO:0010628Inferred only
ATP6V1D decreases the expression of ADAM19ProteinHetionet hetionet:regulates:51382-8728Inferred only
SLC16A3 decreases the expression of ADAM19ProteinHetionet hetionet:regulates:9123-8728Inferred only
UFD1 decreases the expression of ADAM19ProteinHetionet hetionet:regulates:7353-8728Inferred only
ADAM19 requires the cofactor Zn(2+)CompoundUniProt Q9H013Inferred only

Other names

5 names

Resolves to: ADAM19

Also called: ADAM 19MADDAMMeltrin-betaMetalloprotease and disintegrin dendritic antigen markerMLTNB

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