Proteins/UNIPROT:Q5T8D3

ACBD5

ProteinUNIPROT:Q5T8D3

Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters..

Function from UniProtKB (Q5T8D3), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

2 rows

acyl-CoA binding domain containing protein 5 deficiency has a germline basis in ACBD5DiseaseGenCC HGNC:23338|MONDO:0100112Inferred only
retinal dystrophy with leukodystrophy has a germline basis in ACBD5DiseaseGenCC HGNC:23338|MONDO:0030026Inferred only

Statements

14 statements

14 statements · 2 reference databases · Subject: ACBD5 · Sources: Hetionet, Reactome

Order

ACBD5 covaries with CLEC10AProteinHetionet hetionet:covaries:10462-91452Inferred only
UBC interacts with ACBD5ProteinHetionet hetionet:interacts:7316-91452Inferred only
ACBD5 participates in Class I peroxisomal membrane protein importPathwayReactome R-HSA-9603798Inferred only
ACBD5 participates in Fatty acid metabolismPathwayReactome R-HSA-8978868Inferred only
ACBD5 participates in MetabolismPathwayReactome R-HSA-1430728Inferred only
ACBD5 participates in Metabolism of lipidsPathwayReactome R-HSA-556833Inferred only
ACBD5 participates in Peroxisomal lipid metabolismPathwayReactome R-HSA-390918Inferred only
ACBD5 participates in Protein localizationPathwayReactome R-HSA-9609507Inferred only
ACBD5 participates in RHO GTPase cyclePathwayReactome R-HSA-9012999Inferred only
ACBD5 participates in RHOA GTPase cyclePathwayReactome R-HSA-8980692Inferred only
ACBD5 participates in RHOC GTPase cyclePathwayReactome R-HSA-9013106Inferred only
ACBD5 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only

Show the remaining 2

ACBD5 participates in Signaling by Rho GTPasesPathwayReactome R-HSA-194315Inferred only
ACBD5 participates in Signaling by Rho GTPases, Miro GTPases and RHOBTB3PathwayReactome R-HSA-9716542Inferred only

Other names

2 names

Resolves to: ACBD5

Also called: Acyl-CoA-binding domain-containing protein 5KIAA1996

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