Biological process
negative regulation of myotube differentiation
Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
Definition from the Gene Ontology (GO:0010832), read 2026-09-23. CC BY 4.0.
GO:0010832Gene Ontology
What the reference databases state
Statements
11 statements
11 statements · 1 reference database · Subject: negative regulation of myotube differentiation · Sources: gene ontology
- BDNF regulates negative regulation of myotube differentiationProteingene ontology P23560|GO:0010832Inferred only
- BHLHA15 regulates negative regulation of myotube differentiationProteingene ontology Q7RTS1|GO:0010832Inferred only
- BHLHE41 regulates negative regulation of myotube differentiationProteingene ontology Q9C0J9|GO:0010832Inferred only
- CCN3 regulates negative regulation of myotube differentiationProteingene ontology P48745|GO:0010832Inferred only
- CEACAM5 regulates negative regulation of myotube differentiationProteingene ontology P06731|GO:0010832Inferred only
- HDAC4 regulates negative regulation of myotube differentiationProteingene ontology P56524|GO:0010832Inferred only
- HDAC5 regulates negative regulation of myotube differentiationProteingene ontology Q9UQL6|GO:0010832Inferred only
- NKX2-5 regulates negative regulation of myotube differentiationProteingene ontology P52952|GO:0010832Inferred only
- NOTCH1 regulates negative regulation of myotube differentiationProteingene ontology P46531|GO:0010832Inferred only
- RPL3L regulates negative regulation of myotube differentiationProteingene ontology Q92901|GO:0010832Inferred only
- XBP1 regulates negative regulation of myotube differentiationProteingene ontology P17861|GO:0010832Inferred only