Pathway
NADPH regeneration
The conversion of isocitrate to 2-oxoglutarate (alpha-ketoglutarate) with the concomitant synthesis of NADPH from NADP+ is thought to play a significant role in supplying NADPH for other reactions in both the cytosol and the peroxisome. The activity of H6PD (Hexose-6-phosphate dehydrogenase) is thought to play a role in maintaining NADP+: NADPH balance within the endoplasmic reticulum.
REACT:R-HSA-389542Reactome
What the reference databases state
Statements
2 statements
2 statements · 1 reference database · Subject: NADPH regeneration · Sources: Reactome
- ACO1 participates in NADPH regenerationProteinReactome R-HSA-389542Inferred only
- IDH1 participates in NADPH regenerationProteinReactome R-HSA-389542Inferred only