Pathway
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se
Ingested selenic acid (H2SeO4) and selenite (SeO3(2-)) are reduced to hydrogen selenide (H2Se) through a combination of actions involving bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 and 2 (PAPSS1/2), PAPSe reductase (PAPSeR), and thioredoxin reductase 1 (TXNRD1).
REACT:R-HSA-2408550Reactome
What the reference databases state
Statements
3 statements
3 statements · 1 reference database · Subject: Metabolism of ingested H2SeO4 and H2SeO3 into H2Se · Sources: Reactome
- PAPSS1 participates in Metabolism of ingested H2SeO4 and H2SeO3 into H2SeProteinReactome R-HSA-2408550Inferred only
- PAPSS2 participates in Metabolism of ingested H2SeO4 and H2SeO3 into H2SeProteinReactome R-HSA-2408550Inferred only
- TXNRD1 participates in Metabolism of ingested H2SeO4 and H2SeO3 into H2SeProteinReactome R-HSA-2408550Inferred only