Pathway
Inhibition of GNAQ regulated signaling in uveal melanoma
This pathway describes parallel and converging signaling pathways driven by GNAQ (Gαq) in uveal melanoma, and the inhibitory effects of darovasertib and FAKi (FAK inhibitor). Key points from [Arang...
WP:5490
What the reference databases state
Statements
33 statements
33 statements · 1 reference database · Subject: Inhibition of GNAQ regulated signaling in uveal melanoma · Sources: WikiPathways
- AKT1 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- AKT2 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- AKT3 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- GNAQ participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- LATS1 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- LATS2 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- MAPK1 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- MOB1A participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- MTOR participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- PIK3CA participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- PIK3CB participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- PIK3CD participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
Show the remaining 21
- PIK3R1 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- PIK3R2 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- PIK3R3 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- PKN1 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- PKN2 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- PKN3 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- PLCB1 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- PLCB2 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- PLCB3 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- PLCB4 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- PTK2 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- RHOA participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- ROCK1 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- TEAD1 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- TEAD2 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- TEAD3 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- TEAD4 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- TRIO participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- TSC1 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- TSC2 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only
- YAP1 participates in Inhibition of GNAQ regulated signaling in uveal melanomaProteinWikiPathways WP5490Inferred only