Pathway
Free fatty acids regulate insulin secretion
Free fatty acids augment the glucose-triggered secretion of insulin. The augmentation is believed to be due to the additive effects of the activation of the free fatty acid receptor 1 (FFAR1 or GPR40) and the metabolism of free fatty acids within the pancreatic beta cell. This module describes each pathway.
REACT:R-HSA-400451Reactome
What the reference databases state
Statements
11 statements
11 statements · 1 reference database · Subject: Free fatty acids regulate insulin secretion · Sources: Reactome
- ACSL3 participates in Free fatty acids regulate insulin secretionProteinReactome R-HSA-400451Inferred only
- ACSL4 participates in Free fatty acids regulate insulin secretionProteinReactome R-HSA-400451Inferred only
- CD36 participates in Free fatty acids regulate insulin secretionProteinReactome R-HSA-400451Inferred only
- FFAR1 participates in Free fatty acids regulate insulin secretionProteinReactome R-HSA-400451Inferred only
- GNA11 participates in Free fatty acids regulate insulin secretionProteinReactome R-HSA-400451Inferred only
- GNA14 participates in Free fatty acids regulate insulin secretionProteinReactome R-HSA-400451Inferred only
- GNA15 participates in Free fatty acids regulate insulin secretionProteinReactome R-HSA-400451Inferred only
- GNAQ participates in Free fatty acids regulate insulin secretionProteinReactome R-HSA-400451Inferred only
- PLCB1 participates in Free fatty acids regulate insulin secretionProteinReactome R-HSA-400451Inferred only
- PLCB2 participates in Free fatty acids regulate insulin secretionProteinReactome R-HSA-400451Inferred only
- PLCB3 participates in Free fatty acids regulate insulin secretionProteinReactome R-HSA-400451Inferred only