Returned by a PubMed search for theobromine

Elevated Salivary Theobromine and Long-Term Improvement of Periodontal Health in Two Cohort Studies.

Journal of clinical periodontology2026PMID 41388278

Clinical effectiveness of theobromine, Remin Pro, and their combination in managing dentin hypersensitivity: a randomized clinical trial.

BMC oral health2026PMID 42834376

The Effect of Theobromine Supplementation on HDL-c Subclasses (HDL-c2, HDL-c3), HDL-c2/HDL-c3 Ratio, and Gene Expression of PPAR-α and Sirt1 in Subjects With Metabolic Syndrome: A Randomized Controlled Clinical Trial.

Food science & nutrition2025PMID 40672541Also tests theobromine

Exploring the impact of dietary theobromine on endometriosis risk: Evidence from Mendelian randomization and NHANES data.

Medicine2025PMID 41305747

Theobromine is associated with slower epigenetic ageing.

Aging2025PMID 41397115

Comparison of Two Dietary Supplements for Treatment of Uric Acid Renal Lithiasis: Citrate vs. Citrate + Theobromine.

Nutrients2020PMID 32645831

Theobromine consumption does not improve fasting and postprandial vascular function in overweight and obese subjects.

European journal of nutrition2019PMID 29330660Also tests theobromine

Theobromine Does Not Affect Fasting and Postprandial HDL Cholesterol Efflux Capacity, While It Decreases Fasting miR-92a Levels in Humans.

Molecular nutrition & food research2018PMID 29797695

Theobromine for the treatment of persistent cough: a randomised, multicentre, double-blind, placebo-controlled clinical trial.

Journal of thoracic disease2017PMID 28839984

Effect of Theobromine Consumption on Serum Lipoprotein Profiles in Apparently Healthy Humans with Low HDL-Cholesterol Concentrations.

Frontiers in molecular biosciences2017PMID 28971099Also tests theobromine

Psychopharmacology of theobromine in healthy volunteers.

Psychopharmacology2013PMID 23420115Also tests theobromine