Papers about theobromine

Elevated Salivary Theobromine and Long-Term Improvement of Periodontal Health in Two Cohort Studies.

Journal of clinical periodontology2026PMID 41388278Measures theobromine; returned by a PubMed search for theobromine

Acute pre-exercise oral intake of cacao polyphenols attenuates central fatigue development during sustained low-intensity ankle dorsiflexion exercise in healthy young male adults.

Physiological reports2026PMID 42706654Compares against theobromine

Clinical effectiveness of theobromine, Remin Pro, and their combination in managing dentin hypersensitivity: a randomized clinical trial.

BMC oral health2026PMID 42834376Returned by a PubMed search for theobromine

Urine alkalinization for dissolution of uric acid stones and treatment of other urological diseases with a treatment combining potassium magnesium citrate and theobromine.

Archivio italiano di urologia, andrologia2025PMID 40162813Indexed under theobromine in PubMed

Body fat percentage is a key factor in elevated plasma levels of caffeine and its metabolite in women.

PeerJ2025PMID 40511376Indexed under theobromine in PubMed's chemical list

The Effect of Theobromine Supplementation on HDL-c Subclasses (HDL-c2, HDL-c3), HDL-c2/HDL-c3 Ratio, and Gene Expression of PPAR-α and Sirt1 in Subjects With Metabolic Syndrome: A Randomized Controlled Clinical Trial.

Food science & nutrition2025PMID 40672541Tests theobromine; returned by a PubMed search for theobromine

Effects of caffeine and its metabolites, theobromine and theophylline, on performance and physiological parameters in cyclists: A randomized, double-blind, placebo-controlled, crossover trial.

Clinical nutrition ESPEN2025PMID 40850526Indexed under theobromine in PubMed

Exploring the impact of dietary theobromine on endometriosis risk: Evidence from Mendelian randomization and NHANES data.

Medicine2025PMID 41305747Returned by a PubMed search for theobromine

Theobromine is associated with slower epigenetic ageing.

Aging2025PMID 41397115Returned by a PubMed search for theobromine

Pharmacokinetic Profile of Caffeine and Its Two Main Metabolites in Dried Blood Spots After Five Different Oral Caffeine Administration Forms-A Randomized Crossover Study.

International journal of sport nutrition and exercise metabolism2024PMID 38215733Studies theobromine as a target

Effects of Mixing Energy Drinks With Alcohol on Driving-Related Skills.

The international journal of neuropsychopharmacology2022PMID 34338762Measures theobromine

Maternal caffeine intake and DNA methylation in newborn cord blood.

The American journal of clinical nutrition2022PMID 34669932Indexed under theobromine in PubMed's chemical list

Caffeine, Paraxanthine, Theophylline, and Theobromine Content in Human Milk.

Nutrients2022PMID 35683994Indexed under theobromine in PubMed

Determination of caffeine, paraxanthine, theophylline and theobromine in premature infants by HILIC-MS/MS.

Bioanalysis2022PMID 36825935Indexed under theobromine in PubMed's chemical list

Effects of theophylline and theobromine on exercise performance and implications for competition sport: A systematic review.

Drug testing and analysis2021PMID 33188564Indexed under theobromine in PubMed's chemical list

International society of sports nutrition position stand: caffeine and exercise performance.

Journal of the International Society of Sports Nutrition2021PMID 33388079Measures theobromine

Pharmacokinetics of Caffeine: A Systematic Analysis of Reported Data for Application in Metabolic Phenotyping and Liver Function Testing.

Frontiers in pharmacology2021PMID 35280254Measures theobromine

Comparison of Two Dietary Supplements for Treatment of Uric Acid Renal Lithiasis: Citrate vs. Citrate + Theobromine.

Nutrients2020PMID 32645831Returned by a PubMed search for theobromine

Theobromine consumption does not improve fasting and postprandial vascular function in overweight and obese subjects.

European journal of nutrition2019PMID 29330660Tests theobromine; returned by a PubMed search for theobromine

Theobromine Does Not Affect Fasting and Postprandial HDL Cholesterol Efflux Capacity, While It Decreases Fasting miR-92a Levels in Humans.

Molecular nutrition & food research2018PMID 29797695Returned by a PubMed search for theobromine

The effect of a single dose of multivitamin and mineral combinations with and without guaraná on functional brain activity during a continuous performance task.

Nutritional neuroscience2017PMID 25259737Indexed under theobromine in PubMed's chemical list

Health benefits of methylxanthines in neurodegenerative diseases.

Molecular nutrition & food research2017PMID 28074613Indexed under theobromine in PubMed's chemical list

Theobromine for the treatment of persistent cough: a randomised, multicentre, double-blind, placebo-controlled clinical trial.

Journal of thoracic disease2017PMID 28839984Returned by a PubMed search for theobromine

Effect of Theobromine Consumption on Serum Lipoprotein Profiles in Apparently Healthy Humans with Low HDL-Cholesterol Concentrations.

Frontiers in molecular biosciences2017PMID 28971099Tests theobromine; returned by a PubMed search for theobromine

Pregnancy-induced changes in the pharmacokinetics of caffeine and its metabolites.

Journal of clinical pharmacology2016PMID 26358647Indexed under theobromine in PubMed's chemical list

Structure-Bioactivity Relationships of Methylxanthines: Trying to Make Sense of All the Promises and the Drawbacks.

Molecules (Basel, Switzerland)2016PMID 27472311Indexed under theobromine in PubMed's chemical list

Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior.

Human molecular genetics2016PMID 27702941Indexed under theobromine in PubMed's chemical list

Simultaneous multiplexed quantification of caffeine and its major metabolites theobromine and paraxanthine using surface-enhanced Raman scattering.

Analytical and bioanalytical chemistry2015PMID 26345445Indexed under theobromine in PubMed's chemical list

Theobromine, the primary methylxanthine found in Theobroma cacao, prevents malignant glioblastoma proliferation by negatively regulating phosphodiesterase-4, extracellular signal-regulated kinase, Akt/mammalian target of rapamycin kinase, and nuclear factor-kappa B.

Nutrition and cancer2014PMID 24547961Indexed under theobromine in PubMed's chemical list

Dietary nutrients associated with short and long sleep duration. Data from a nationally representative sample.

Appetite2013PMID 23339991Indexed under theobromine in PubMed's chemical list

Psychopharmacology of theobromine in healthy volunteers.

Psychopharmacology2013PMID 23420115Tests theobromine; returned by a PubMed search for theobromine

Measurement of CYP1A2 activity: a focus on caffeine as a probe.

Current drug metabolism2012PMID 22554278Indexed under theobromine in PubMed's chemical list

Pharmacokinetics and metabolism of natural methylxanthines in animal and man.

Handbook of experimental pharmacology2011PMID 20859793Indexed under theobromine in PubMed's chemical list

A double-blind, placebo-controlled, multi-dose evaluation of the acute behavioural effects of guaraná in humans.

Journal of psychopharmacology (Oxford, England)2007PMID 16533867Indexed under theobromine in PubMed's chemical list

Caffeine metabolites in umbilical cord blood, cytochrome P-450 1A2 activity, and intrauterine growth restriction.

American journal of epidemiology2006PMID 16641310Indexed under theobromine in PubMed's chemical list

Population pharmacokinetics of caffeine and its metabolites theobromine, paraxanthine and theophylline after inhalation in combination with diacetylmorphine.

Basic & clinical pharmacology & toxicology2005PMID 15667599Indexed under theobromine in PubMed's chemical list

Serum metabolite/caffeine ratios as a test for liver function.

Journal of clinical pharmacology2004PMID 15051740Indexed under theobromine in PubMed's chemical list

Antagonism of adenosine receptors by caffeine and caffeine metabolites in equine forebrain tissues.

American journal of veterinary research2003PMID 12602592Indexed under theobromine in PubMed's chemical list

Pharmacology of ephedra alkaloids and caffeine after single-dose dietary supplement use.

Clinical pharmacology and therapeutics2002PMID 12087345Indexed under theobromine in PubMed's chemical list

Caffeine potentiates the discriminative-stimulus effects of nicotine in rats.

Psychopharmacology2002PMID 12172692Indexed under theobromine in PubMed's chemical list

Comparison of the potency of adenosine as an agonist at human adenosine receptors expressed in Chinese hamster ovary cells.

Biochemical pharmacology2001PMID 11226378Indexed under theobromine in PubMed's chemical list

Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease.

The Journal of neuroscience2001PMID 11319241Indexed under theobromine in PubMed's chemical list

An herbal supplement containing Ma Huang-Guarana for weight loss: a randomized, double-blind trial.

International journal of obesity and related metabolic disorders2001PMID 11319627Indexed under theobromine in PubMed's chemical list

Chronic effects of xanthines on levels of central receptors in mice.

Cellular and molecular neurobiology1999PMID 10456233Indexed under theobromine in PubMed's chemical list

Inhibition of melanoma pulmonary metastasis by methylxanthines due to decreased invasion and proliferation.

Melanoma research1998PMID 9610865Indexed under theobromine in PubMed's chemical list

Recent advances in caffeine and theobromine toxicities: a review.

Plant foods for human nutrition (Dordrecht, Netherlands)1997PMID 9629863Indexed under theobromine in PubMed's chemical list

Absorption rate of methylxanthines following capsules, cola and chocolate.

European journal of clinical pharmacology1996PMID 9010706Indexed under theobromine in PubMed's chemical list

Adenosine antagonists potentiate D2 dopamine-dependent activation of Fos in the striatopallidal pathway.

Neuroscience1995PMID 8577368Indexed under theobromine in PubMed's chemical list

Discriminative stimulus and subjective effects of theobromine and caffeine in humans.

Psychopharmacology1994PMID 7862879Indexed under theobromine in PubMed's chemical list

Caffeine metabolism by human hepatic cytochromes P450: contributions of 1A2, 2E1 and 3A isoforms.

Biochemical pharmacology1994PMID 8204093Indexed under theobromine in PubMed's chemical list