tetradecanal

Three steps

• 1-tetradecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
  1. H2O[r] + NAD+[r] + tetradecanal[r] = 2 H+[r] + myristic acid[r] + NADH[r]
  2. long-chain-fatty-acid-CoA ligase (myristic acid)
  3. 2-(9Z-octadecenoyl)-glycerol + tetradecanoyl-CoA = 1-tetradecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA

  Catalysed by ALDH3A2, SLC27A2, ACSL4, ACSL3 and 7 moreendoplasmic reticulum, cytosol

• (11Z,14Z)-eicosadienoateReach from here →
  1. H2O[r] + NAD+[r] + tetradecanal[r] = 2 H+[r] + myristic acid[r] + NADH[r]
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ALDH3A2endoplasmic reticulum, cytosol, extracellular spaceOne of 12 routes

• (17Z)-hexacosenoateReach from here →
  1. H2O[r] + NAD+[r] + tetradecanal[r] = 2 H+[r] + myristic acid[r] + NADH[r]
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ALDH3A2endoplasmic reticulum, cytosol, extracellular spaceOne of 12 routes

• (7Z,10Z,13Z,16Z,19Z)-docosapentaenoateReach from here →
  1. H2O[r] + NAD+[r] + tetradecanal[r] = 2 H+[r] + myristic acid[r] + NADH[r]
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ALDH3A2endoplasmic reticulum, cytosol, extracellular spaceOne of 12 routes

• (7Z,10Z,13Z,16Z)-docosatetraenoateReach from here →
  1. H2O[r] + NAD+[r] + tetradecanal[r] = 2 H+[r] + myristic acid[r] + NADH[r]
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ALDH3A2endoplasmic reticulum, cytosol, extracellular spaceOne of 12 routes

• (5Z,8Z,11Z)-eicosatrienoateReach from here →
  1. H2O[r] + NAD+[r] + tetradecanal[r] = 2 H+[r] + myristic acid[r] + NADH[r]
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ALDH3A2endoplasmic reticulum, cytosol, extracellular spaceOne of 12 routes

• tricosanoateReach from here →
  1. H2O[r] + NAD+[r] + tetradecanal[r] = 2 H+[r] + myristic acid[r] + NADH[r]
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ALDH3A2endoplasmic reticulum, cytosol, extracellular spaceOne of 12 routes

• O-tetradecanoyl-(R)-carnitineReach from here →
  1. H2O[r] + NAD+[r] + tetradecanal[r] = 2 H+[r] + myristic acid[r] + NADH[r]
  2. long-chain-fatty-acid-CoA ligase (myristic acid)
  3. tetradecanoyl-CoA + (R)-carnitine = O-tetradecanoyl-(R)-carnitine + CoA

  Catalysed by ALDH3A2, SLC27A2, ACSL4, ACSL3 and 6 moreendoplasmic reticulum, cytosol

• (5Z)-tetradecenoyl-CoAReach from here →
  1. H2O[r] + NAD+[r] + tetradecanal[r] = 2 H+[r] + myristic acid[r] + NADH[r]
  2. long-chain-fatty-acid-CoA ligase (myristic acid)
  3. stearoyl-CoA 9-desaturase (myristoyl-CoA)

  Catalysed by ALDH3A2, SLC27A2, ACSL4, ACSL3 and 7 moreendoplasmic reticulum, cytosol

• N-tetradecanoylglycineReach from here →
  1. H2O[r] + NAD+[r] + tetradecanal[r] = 2 H+[r] + myristic acid[r] + NADH[r]
  2. long-chain-fatty-acid-CoA ligase (myristic acid)
  3. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)

  Catalysed by ALDH3A2, SLC27A2, ACSL4, ACSL3 and 6 moreendoplasmic reticulum, cytosol