1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine
362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API
352 compounds within 3 steps: 6 in 1, 77 in 2, 269 in 3
Three steps
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
- prostaglandin-endoperoxide synthase (arachidonate)
- prostaglandin H2 + reduced [NADPH--hemoprotein reductase] + O2 = 19-hydroxyprostaglandin H2 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by PLA2G6, PLA2G4B, PLA2G2A, PLA2G5 and 12 morecytosol
- 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
- transport of arachidonate (cytosol to extracellular)
- solute carrier organic anion transporter (S-glutathionyl-2-4-dinitrobenzene)
Catalysed by PLA2G6, PLA2G4B, PLA2G2A, PLA2G5 and 13 moreextracellular space, cytosolOne of 4 routes