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carnosineFinding

Carnosine has no detected effect on tumour necrosis factor alpha concentration

no difference foundModerate evidenceFinding

01 · The sentence it was drawn from

“There were no significant differences in changes in MCP-1, CRP, IL-6, IL-10, and TNF-α levels between the carnosine and placebo groups.”

Quoted verbatim from Carnosine Supplementation Has No Effect on Inflammatory Markers in Adults with Prediabetes and Type 2 Diabetes: A Randomised Controlled Trial.

This finding among the 70 findings on its endpoint

carnosine

Tumour necrosis factor alpha concentration

no difference found

Who: n = 41 · Adults with prediabetes or well-controlled type 2 diabetes (diet or metformin only), per-protocol analysis of 19 carnosine and 22 placebo
Dose studied: 2 g/day carnosine for 14 weeks versus matching placebo

Moderate evidencePMID 39599686 · 2024

02 · The study

Study: RCT
Participants: 41
Duration: 3 months

Evidence, by strength

strong
moderatethis finding
limited
very limited
insufficient

03 · The paper

Nutrients

Carnosine Supplementation Has No Effect on Inflammatory Markers in Adults with Prediabetes and Type 2 Diabetes: A Randomised Controlled Trial.

2024PMID 39599686doi 10.3390/nu16223900

What else it reported3 findings · 1 compound · 3 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M71QR0F1DRHFTXFQ37YC59NG