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Catalyst

L-methionineFinding

L-methionine decreases colorectal cancer incidence

lowersLimited evidenceFinding

01 · The sentence it was drawn from

“For methionine intake, an inverse association was observed with incident CRC overall (RR = 0.72; 95% CI = 0.54–0.96; p trend = 0.03 for comparison of extreme quartiles) that appeared to be driven by a greater reduction in distal than proximal CRC risk.”
Quoted verbatim from Associations between intake of folate and related micronutrients with molecularly defined colorectal cancer risks in the Iowa Women's Health Study.
This finding among the 22 findings on its endpoint

L-methionine

Colorectal cancer incidence

lowers

Effect as reported

0.72risk ratio

CI 0.54 to 0.96

Who
Women aged 55-69 years at baseline in the Iowa Women's Health Study (analytic cohort of 35,216); highest versus lowest quartile of methionine intake
Dose studied
dietary methionine intake (food and supplements) from a baseline semi-quantitative food frequency questionnaire; quartiles, extreme quartiles compared

Limited evidencePMID 23061900 · 2012

02 · The study

Study
cohort
Duration
not reported

Evidence, by strength

  • strong
  • moderate
  • limitedthis finding
  • very limited
  • insufficient

03 · The paper

Nutrition and cancer
What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M70E2Z93T107SQPGWCQ52V94