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PapersPMID:23061900

Associations between intake of folate and related micronutrients with molecularly defined colorectal cancer risks in the Iowa Women's Health Study.

Nutrition and cancer2012The record ↗

  1. Finding, limited evidencelowersColorectal cancer incidence

What moved

1 findingHow to read these marks →
  • “For methionine intake, an inverse association was observed with incident CRC overall (RR = 0.72; 95% CI = 0.54–0.96; p trend = 0.03 for comparison of extreme quartiles) that appeared to be driven by a greater reduction in distal than proximal CRC risk.”
    Study
    cohort
    Effect
    0.72 risk ratio, 95% CI 0.54 to 0.96
    Dose studied
    dietary methionine intake (food and supplements) from a baseline semi-quantitative food frequency questionnaire; quartiles, extreme quartiles compared
    Population
    Women aged 55-69 years at baseline in the Iowa Women's Health Study (analytic cohort of 35,216); highest versus lowest quartile of methionine intake

Study record

Design
cohort study
Species
human
Population
Iowa Women's Health Study participants, women aged 55-69 years at baseline, analytic cohort of 35,216 women
Participants
35,216
Comparator
observational
Duration
not reported
Endpoints measured
26