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Catalyst

L-phenylalanineFinding

L-phenylalanine increases plasma glucagon

raisesModerate evidenceFinding

01 · The sentence it was drawn from

“Phe-10 g increased (p = 0.002), while Phe-5 g tended to increase (p = 0.097), plasma glucagon AUC−1 to −120 min, compared with control.”
Quoted verbatim from Effects of L-Phenylalanine on Energy Intake and Glycaemia-Impacts on Appetite Perceptions, Gastrointestinal Hormones and Gastric Emptying in Healthy Males.
This finding among the 2 findings on its endpoint

L-phenylalanine

Plasma glucagon

raises

Who
Healthy normal-weight young men, part B, randomised double-blind three-way crossover; plasma glucagon AUC over 120 min after a mixed-nutrient drink preceded by the intragastric bolus; Phe-10 g arm against control suspension
Dose studied
10 g L-phenylalanine as a single 100-mL intragastric bolus via nasogastric tube, suspended in ORA-Plus, 30 min before the mixed-nutrient drink

Moderate evidencePMID 32560181 · 2020

02 · The study

Study
RCT
Duration
1 day

Evidence, by strength

  • strong
  • moderatethis finding
  • limited
  • very limited
  • insufficient

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M70CSN38WPCJ7DH0SSX4NWZZ