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Catalyst

L-histidineFinding

L-histidine decreases subjective fatigue

lowersVery limited evidenceFinding

01 · The sentence it was drawn from

“The fatigue T-scores on the POMS test decreased significantly following histidine ingestion compared to placebo ingestion (p<0.05).”
Quoted verbatim from The effect of histidine on mental fatigue and cognitive performance in subjects with high fatigue and sleep disruption scores.
This finding among the 10 findings on its endpoint

L-histidine

Subjective fatigue

lowers

Who
Adults selected for high fatigue and sleep disruption scores; double-blind crossover against placebo
Dose studied
histidine ingested daily for two weeks (dose not stated in abstract)

Very limited evidencePMID 25921948 · 2015

02 · The study

Study
crossover
Duration
14 days

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M706PTR27YTMFGQJ3F4ACZDT