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Catalyst

cholineFinding

Choline increases all-cause mortality

raisesVery limited evidenceFindingreplicated ×1

01 · The sentence it was drawn from

“The linear dose-response analysis showed that each 100 mg/day increase in choline intake was significantly associated with 6% and 11% increases in risk of all-cause (RR = 1.06, 95% CI: 1.03, 1.10, I2 =83.7%, P < .001) and cardiovascular diseases mortality (RR = 1.11, 95% CI: 1.06, 1.16, I2 = 54.3%, P = .02) respectively.”
Quoted verbatim from Higher dietary choline intake is associated with increased risk of all-cause and cause-specific mortality: A systematic review and dose-response meta-analysis of cohort studies.
This finding among the 156 findings on its endpoint

choline

All-cause mortality

raises

Effect as reported

1.06risk ratio

CI 1.03 to 1.1

Who
Participants in six prospective cohort studies of habitual dietary choline intake; linear dose-response per 100 mg/day
Dose studied
each 100 mg/day increase in dietary choline intake

Very limited evidencePMID 39341000 · 2024

02 · The study

Study
meta-analysis
Duration
not reported

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

03 · The paper

Nutrition research (New York, N.Y.)
What else it reported2 findings · 1 compound · 2 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M701ZGM4A9KX52Z61G44A6QC