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Catalyst

cholineFinding

Choline increases colorectal cancer incidence

raisesInsufficient evidenceFinding

01 · The sentence it was drawn from

“Serum choline was strongly and statistically significantly associated with incident colorectal cancer risk (Table 3); participants with higher serum choline had greater risk of developing colorectal cancer over the ensuing follow-up period (P-trend<0.0001).”
Quoted verbatim from Serum Trimethylamine N-oxide, Carnitine, Choline, and Betaine in Relation to Colorectal Cancer Risk in the Alpha Tocopherol, Beta Carotene Cancer Prevention Study.
This finding among the 22 findings on its endpoint

choline

Colorectal cancer incidence

raises

Who
Male Finnish smokers aged 50-69 in the ATBC Study; nested case-control of incident colorectal cancer cases and matched controls, baseline fasting serum choline by quartile, median follow-up 14 years
Dose studied
not reported

Insufficient evidencePMID 28077427 · 2017

02 · The study

Study
case-control
Duration
not reported

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limited
  • insufficientthis finding

03 · The paper

Cancer epidemiology, biomarkers & prevention
What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M7017J47GFTN7SR4M9HV2CKM