PapersPMID:28077427
Serum Trimethylamine N-oxide, Carnitine, Choline, and Betaine in Relation to Colorectal Cancer Risk in the Alpha Tocopherol, Beta Carotene Cancer Prevention Study.
cholineWhat moved
1 findingHow to read these marks →- Increases colorectal cancer incidence
insufficient
“Serum choline was strongly and statistically significantly associated with incident colorectal cancer risk (Table 3); participants with higher serum choline had greater risk of developing colorectal cancer over the ensuing follow-up period (P-trend<0.0001).”
- Study
- case-control
- Interests
- Industry funded
- Population
- Male Finnish smokers aged 50-69 in the ATBC Study; nested case-control of incident colorectal cancer cases and matched controls, baseline fasting serum choline by quartile, median follow-up 14 years
Study record
- Design
- case-control study
- Species
- human
- Population
- Male Finnish smokers in the ATBC trial, nested case-control of incident colorectal cancer cases and matched controls
- Participants
- 1,288
- Comparator
- observational
- Duration
- not reported
- Endpoints measured
- 11