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cyanocob(III)alaminFinding

cyanocob(III)alamin increases all-cause mortality

raisesVery limited evidenceFinding

01 · The sentence it was drawn from

“The meta-analysis of cohort studies showed a positive association between a high serum vitamin B12 concentration (>600 pmol/L) and all-cause mortality (adjusted HR 1.50, 95 % CI 1.29 to 1.74; n = 10; p < 0.01), CVD mortality (adjusted HR 2.04, 95 % CI 0.99 to 4.19; n = 2; p = 0.02), except cancer mortality (adjusted HR 1.56, 95 % CI 0.82 to 2.95; n = 3).”
Quoted verbatim from The origin of vitamin B12 levels and risk of all-cause, cardiovascular and cancer specific mortality: A systematic review and dose-response meta-analysis.
This finding among the 156 findings on its endpoint

cyanocob(III)alamin

All-cause mortality

raises

Effect as reported

1.5hazard ratio

CI 1.29 to 1.74

Who
Pooled cohort studies of adults; high circulating serum vitamin B12 category (>600 pmol/L) versus the reference category; no one was dosed
Dose studied
not reported

Very limited evidencePMID 38252787 · 2024

02 · The study

Study
meta-analysis
Duration
not reported

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

03 · The paper

Archives of gerontology and geriatrics
What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6ZWWCXSRBNB8X6K4T7V0Q2C