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Eleutherococcus senticosusFinding

Eleutherococcus senticosus decreases serum creatinine concentration

lowersVery limited evidenceFinding

01 · The sentence it was drawn from

“Interestingly, the ES extract supplementation mitigated this increase–creatinine was lower at both doses than with paracetamol alone, with the effect at the 750 mg/kg dose (with levels similar to the control group) and slightly weaker at the 1500 mg/kg dose.”
Quoted verbatim from Hepatoprotective Activity of the Fruits of Eleutherococcus senticosus in Acetaminophen-Induced Liver Injury in Mice and Their Chemical Composition.
This finding among the 19 findings on its endpoint

Eleutherococcus senticosus

Serum creatinine concentration

lowers

Who
Female BALB/c mice given paracetamol 300 mg/kg intraperitoneally on day 8 to induce acute liver injury; E. senticosus fruit extract at 750 or 1500 mg/kg orally before the challenge, against paracetamol alone (paracetamol given to every treated arm); both doses together
Dose studied
750 or 1500 mg/kg by gavage twice daily for 7 days and once on day 8

Very limited evidencePMID 41228527 · 2025

02 · The study

Study
animal · not in humans
Duration
8 days

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

03 · The paper

Nutrients
What else it reported1 finding · 0 compounds · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6ZW97HA6H8Q3EZHMH68FTY0