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Eleutherococcus senticosusFinding

Eleutherococcus senticosus decreases tumour necrosis factor alpha concentration

lowersVery limited evidenceFindingreplicated ×1

01 · The sentence it was drawn from

“Compared with the LPS model group, ASTF significantly reduced the contents of IL-1β, IL-6, PGE2 and TNF-α in each dosage group (P<0.001), and except for the content of IL-1β, all of these effects were dose-dependent.”
Quoted verbatim from Acanthopanax senticosus total flavonoids alleviate lipopolysaccharide-induced intestinal inflammation and modulate the gut microbiota in mice.
This finding among the 70 findings on its endpoint

Eleutherococcus senticosus

Tumour necrosis factor alpha concentration

lowers

Who
Male Kunming mice with intestinal inflammation induced by intraperitoneal LPS 10 mg/kg; serum TNF-α by ELISA after 7 days of treatment; all three ASTF dose groups (200, 400, 800 mg/kg) against the LPS model group
Dose studied
200, 400 or 800 mg/kg once daily by intragastric gavage for 7 days after the LPS injection

Very limited evidencePMID 35088071 · 2022

02 · The study

Study
animal · not in humans
Duration
7 days

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

03 · The paper

Bioscience reports
What else it reported2 findings · 0 compounds · 2 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6ZW9607Z4APSCG9YW9CPD8R