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Catalyst

cholineFinding

Choline decreases colorectal cancer incidence

lowersVery limited evidenceFinding

01 · The sentence it was drawn from

“We found an inverse association between choline and CRC risk, with an OR for the highest versus the lowest tertile of 0.81 (95%CI: 0.71–0.93), with a significant trend in risk across tertiles.”
Quoted verbatim from Dietary choline and sphingomyelin choline moiety intake and risk of colorectal cancer: a case-control study.
This finding among the 22 findings on its endpoint

choline

Colorectal cancer incidence

lowers

Effect as reported

0.81odds ratio

CI 0.71 to 0.93

Who
1953 histologically proven colorectal cancer cases and 4154 hospital controls without cancer, six Italian centres, 1992-1996; usual dietary choline by food-frequency questionnaire; highest versus lowest energy-adjusted tertile
Dose studied
dietary choline, energy-adjusted tertiles based on the control distribution; control mean 400.7 mg/day

Very limited evidencePMID 37479807 · 2023

02 · The study

Study
case-control
Duration
not reported

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

03 · The paper

European journal of clinical nutrition
What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6ZVJD668R0MJK44BWTVH7X5