PapersPMID:37479807
Dietary choline and sphingomyelin choline moiety intake and risk of colorectal cancer: a case-control study.
cholineWhat moved
1 findingHow to read these marks →- Decreases colorectal cancer incidence
very limited
“We found an inverse association between choline and CRC risk, with an OR for the highest versus the lowest tertile of 0.81 (95%CI: 0.71–0.93), with a significant trend in risk across tertiles.”
- Study
- case-control
- Effect
- 0.81 odds ratio, 95% CI 0.71 to 0.93
- Dose studied
- dietary choline, energy-adjusted tertiles based on the control distribution; control mean 400.7 mg/day
- Population
- 1953 histologically proven colorectal cancer cases and 4154 hospital controls without cancer, six Italian centres, 1992-1996; usual dietary choline by food-frequency questionnaire; highest versus lowest energy-adjusted tertile
Study record
- Design
- case-control study
- Species
- human
- Population
- Incident colorectal cancer cases and hospital controls, six Italian centers, 1992-1996
- Participants
- 6,107
- Comparator
- observational
- Duration
- not reported
- Endpoints measured
- 12