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Olea europaeaFinding

Olea europaea has no detected effect on tumour necrosis factor alpha concentration

no difference foundLimited evidenceFinding

01 · The sentence it was drawn from

“Subjects on OLE also experienced a 32% increase in interleukin-6 (p = 0.014), but there were no observed changes in interleukin-8, TNF-α, or ultra-sensitive CRP (Table 3).”
Quoted verbatim from Olive (Olea europaea L.) leaf polyphenols improve insulin sensitivity in middle-aged overweight men: a randomized, placebo-controlled, crossover trial.
This finding among the 70 findings on its endpoint

Olea europaea

Tumour necrosis factor alpha concentration

no difference found

Who
45 overweight men aged 35-55 years analysed by intention to treat in a randomised double-blind crossover (12 weeks each arm, 6-week washout); placebo capsules held safflower oil only
Dose studied
four capsules once daily for 12 weeks, 51.1 mg oleuropein and 9.7 mg hydroxytyrosol per day

Limited evidencePMID 23516412 · 2013

02 · The study

Study
crossover
Duration
3 months

Evidence, by strength

  • strong
  • moderate
  • limitedthis finding
  • very limited
  • insufficient

03 · The paper

PloS one
What else it reported3 findings · 0 compounds · 3 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6ZTC0KGMED9DE3W0FB8JY4P