PapersPMID:23516412
Olive (Olea europaea L.) leaf polyphenols improve insulin sensitivity in middle-aged overweight men: a randomized, placebo-controlled, crossover trial.
- findings
- 3
- compound
- 1
- endpoints
- 3
- no difference found
- 2
- Study, every finding
- crossover · 3 months
- Dose studied, every finding
- four capsules once daily for 12 weeks, 51.1 mg oleuropein and 9.7 mg hydroxytyrosol per day
- Population, every finding
- 45 overweight men aged 35-55 years analysed by intention to treat in a randomised double-blind crossover (12 weeks each arm, 6-week washout); placebo capsules held safflower oil only
What moved
How to read these marks →“Subjects on OLE also experienced a 32% increase in interleukin-6 (p = 0.014), but there were no observed changes in interleukin-8, TNF-α, or ultra-sensitive CRP (Table 3).”
Study record
- Design
- crossover trial
- Species
- human
- Population
- Overweight men aged 35-55 years (BMI 25-30 kg/m2), Auckland, New Zealand
- Participants
- 46
- Comparator
- placebo
- Duration
- 84 days
- Endpoints measured
- 51