Skip to content
Catalyst

N,N-dimethylethanolamineFinding

N,N-dimethylethanolamine decreases alanine aminotransferase

lowersInsufficient evidenceFinding

01 · The sentence it was drawn from

“2-Dimethylaminoethanol (DMAE; 0.1--0.5 g/kg) significantly reduced the paracetamol-induced increments of serum-enzyme activities (GOT, GPT, SDH) in rats and mice.”
Quoted verbatim from [Influence of 2-dimethylaminoethanol on the hepatotoxicity of paracetamol in rats and mice (author's transl)].
This finding among the 65 findings on its endpoint

N,N-dimethylethanolamine

Alanine aminotransferase

lowers

Who
Rats and mice with paracetamol-induced liver injury; findings in rodents, not humans
Dose studied
0.1-0.5 g/kg

Insufficient evidencePMID 582737 · 1979

02 · The study

Study
animal · not in humans
Duration
not reported

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limited
  • insufficientthis finding

03 · The paper

Arzneimittel-Forschung
What else it reported2 findings · 1 compound · 2 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6ZT0PMS03YWYFHKKAY5RSXJ