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Catalyst

nicotinic acidFinding

Nicotinic acid decreases total cholesterol (TC)

lowersModerate evidenceFinding

01 · The sentence it was drawn from

“The pooled results suggested that niacin supplementation significantly reduced the level of TC (WMD, −0.28; 95% CI, −0.44 to −0.12; P =.001), and that significant heterogeneity was detected across the included trials (I 2 = 74.0%; P =.002).”
Quoted verbatim from Effectiveness of niacin supplementation for patients with type 2 diabetes: A meta-analysis of randomized controlled trials.
This finding among the 116 findings on its endpoint

nicotinic acid

Total cholesterol (TC)

lowers

Effect as reported

−0.28mean difference

CI −0.44 to −0.12

Who
Adults with type 2 diabetes in eight randomised trials (2110 patients in the review), pooled across niacin doses and formulations; three trials added niacin to a statin given in both arms; control was placebo or no treatment with the same background therapy
Dose studied
not reported

Moderate evidencePMID 32702899 · 2020

02 · The study

Study
meta-analysis
Duration
not reported

Evidence, by strength

  • strong
  • moderatethis finding
  • limited
  • very limited
  • insufficient

03 · The paper

Medicine
What else it reported3 findings · 1 compound · 3 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6ZGWAB3GR4S6746N7E8XN84