Skip to content
Catalyst

bovine colostrumFinding

Bovine colostrum decreases C-reactive protein concentration

lowersModerate evidenceFinding

01 · The sentence it was drawn from

“Amongst secondary biomarker endpoints (Table 4), compared with standard care, budesonide reduced plasma CRP (mean reduction 5.2 mg/L; 90%CI 0.8, 9.6; P = 0.05) and sCD163 (mean reduction 405 ng/mL; 90%CI 73, 738; P = 0.05) while colostrum and N-acetyl glucosamine had effects only on CRP (reductions 5.9 mg/L; 90%CI 1.4, 10.3; P = 0.03, and 4.8 mg/L; 90%CI 0.5, 9.2; P = 0.07, respectively).”
Quoted verbatim from Malnutrition enteropathy in Zambian and Zimbabwean children with severe acute malnutrition: A multi-arm randomized phase II trial.
This finding among the 114 findings on its endpoint

bovine colostrum

C-reactive protein concentration

lowers

Who
Children aged 6-59 months hospitalised with complicated severe acute malnutrition in Zambia and Zimbabwe; colostrum added to standard care and compared with standard care only; day 15 plasma CRP, per-protocol ANCOVA against standard care
Dose studied
1.5 g 8-hourly (4.5 g/day), orally or by nasogastric tube, 14 days

Moderate evidencePMID 38632262 · 2024

02 · The study

Study
RCT
Duration
14 days

Evidence, by strength

  • strong
  • moderatethis finding
  • limited
  • very limited
  • insufficient

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6ZBYF06N0DKKPHWCQ02X4N5