bovine colostrumFinding
Bovine colostrum decreases C-reactive protein concentration
lowersModerate evidenceFinding
01 · The sentence it was drawn from
“Amongst secondary biomarker endpoints (Table 4), compared with standard care, budesonide reduced plasma CRP (mean reduction 5.2 mg/L; 90%CI 0.8, 9.6; P = 0.05) and sCD163 (mean reduction 405 ng/mL; 90%CI 73, 738; P = 0.05) while colostrum and N-acetyl glucosamine had effects only on CRP (reductions 5.9 mg/L; 90%CI 1.4, 10.3; P = 0.03, and 4.8 mg/L; 90%CI 0.5, 9.2; P = 0.07, respectively).”
bovine colostrum
C- reactive protein concentration
lowers
- Who
- Children aged 6-59 months hospitalised with complicated severe acute malnutrition in Zambia and Zimbabwe; colostrum added to standard care and compared with standard care only; day 15 plasma CRP, per-protocol ANCOVA against standard care
- Dose studied
- 1.5 g 8-hourly (4.5 g/day), orally or by nasogastric tube, 14 days
Moderate evidencePMID 38632262 · 2024
02 · The study
- Study
- RCT
- Duration
- 14 days
Evidence, by strength
- strong
- moderatethis finding
- limited
- very limited
- insufficient
03 · The paper
Nature communications2024PMID 38632262doi 10.1038/s41467-024-45528-0An author is affiliated with a producer
04 · To cite this finding
This address does not changehttps://catalystproject.ai/e/01M6ZBYF06N0DKKPHWCQ02X4N5