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magnesium(2+)Finding

Magnesium(2+) decreases visual analogue scale pain intensity

lowersModerate evidenceFindingreplicated ×4

01 · The sentence it was drawn from

“As shown in Fig. 4, IA Mg was associated with significantly lower VAS scores at postoperative 2 h (MD = − 0.46, 95% CI: − 0.64 to − 0.27; p = 0.14; I2 = 39%), 4 h (MD = − 0.85, 95% CI: − 1.40 to − 0.30; p < 0.0001; I2 = 95%), 12 h (MD = − 0.83, 95% CI: − 1.17 to − 0.48; p = 0.004; I2 = 71%), and 24 h (MD = − 0.58, 95% CI: − 0.79 to − 0.36; p = 0.05; I2 = 45%) (Table 2).”
Quoted verbatim from Intra-articular magnesium to alleviate postoperative pain after arthroscopic knee surgery: a meta-analysis of randomized controlled trials.
This finding among the 19 findings on its endpoint

magnesium(2+)

Visual analogue scale pain intensity

lowers

Effect as reported

−0.58mean difference

CI −0.79 to −0.36

Who
Adults after arthroscopic knee surgery; pooled randomised trials of intra-articular magnesium (alone or with a local anaesthetic) against saline or the same local anaesthetic alone; pain with movement on a 0-10 VAS, 24 hours after surgery
Dose studied
intra-articular magnesium, per-trial doses from 0.15 g to 1.5 g in 10 to 30 mL (one trial 10 mg/kg)

Moderate evidencePMID 33546717 · 2021

02 · The study

Study
meta-analysis
Duration
not reported

Evidence, by strength

  • strong
  • moderatethis finding
  • limited
  • very limited
  • insufficient

03 · The paper

Journal of orthopaedic surgery and research
What else it reported2 findings · 1 compound · 2 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6Y3CWZ50AP8Y54V30FA212Q