Skip to content
Catalyst

L-arginineFinding

L-arginine decreases asymmetric dimethylarginine (ADMA) concentration

lowersVery limited evidenceFinding

01 · The sentence it was drawn from

“Malaria-infected dams receiving L-arginine supplementation showed reduced serum ADMA (P < 0.01; Fig. 5B) and SDMA (P < 0.05; Fig. 5C), although there was no significant difference in L-arginine/ADMA ratio (P > 0.05; Fig. 5D) compared with the control group.”
Quoted verbatim from Malaria in pregnancy alters l-arginine bioavailability and placental vascular development.
This finding among the 2 findings on its endpoint

L-arginine

Asymmetric dimethylarginine (ADMA) concentration

lowers

Who
Pregnant BALB/c mice infected with Plasmodium berghei ANKA on gestational day 13 (experimental malaria in pregnancy), serum at gestational day 19; malaria-infected dams only
Dose studied
1.2% L-arginine monohydrochloride in drinking water versus regular drinking water, started before pregnancy and at least 13 days before infection

Very limited evidencePMID 29514999 · 2018

02 · The study

Study
animal · not in humans
Duration
not reported

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

03 · The paper

Science translational medicine
What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6XKZKQ07R5JG945JX2G86GR