Inulin increases alanine aminotransferase

raisesModerate evidenceFinding

01 · The sentence it was drawn from

“Linear regression analysis revealed that the levels of AST and ALT at T2 were higher in the inulin group than in the placebo group (Linear regression models β = 8.55, 95% CI [2.33; 14.77], p = 0.008 and β = 6.01, 95% CI [2.02; 10.00] p = 0.004 respectively; Table 3).”

Quoted verbatim from Liver alterations are not improved by inulin supplementation in alcohol use disorder patients during alcohol withdrawal: A pilot randomized, double-blind, placebo-controlled study.

This finding among the 65 findings on its endpoint

inulin

Alanine aminotransferase

raises

Who: Adults with alcohol use disorder hospitalised for a 3-week alcohol detoxification program, whole sample; adjusted for sex, ethanol consumed in week 2 and the baseline value; measured at day 19 after 17 days of supplementation
Dose studied: inulin increased from 4 g/d to 8 g/d to 16 g/d over 17 days, against maltodextrin placebo on the same schedule

Moderate evidencePMID 35490461 · 2022

02 · The study

Study: RCT
Duration: 17 days

Evidence, by strength

strong
moderatethis finding
limited
very limited
insufficient

03 · The paper

EBioMedicine

Liver alterations are not improved by inulin supplementation in alcohol use disorder patients during alcohol withdrawal: A pilot randomized, double-blind, placebo-controlled study.

2022PMID 35490461doi 10.1016/j.ebiom.2022.104033

What else it reported3 findings · 0 compounds · 3 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6XJ6BHM7268JM4VAFD9SG90