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calciol/Finding

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A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.

  • calciol — decreases interleukin-6 concentration

    Evidence strength: very limited.Findingreplicated ×1
    “Additionally, we observed a significant reduction in high-sensitivity C-reactive protein levels after 3 months (median: 0.62 [0.05 to 29.6] mg/L vs. 0.32 [0.02 to 3.13] mg/L; P = .02) and after 6 months (median: 0.62 [0.05 to 29.6] mg/L vs. 0.50 [0.02 to 5.66] mg/L; P = .04) of cholecalciferol supplementation, as well as a significant reduction in interleukin-6 levels (median: 6.44 pg/mL vs. 3.83 pg/mL; P = .018) after 6 months of supplementation.”
    Quoted verbatim from Impact of cholecalciferol treatment on biomarkers of inflammation and myocardial structure in hemodialysis patients without hyperparathyroidism..
    Study
    cohort
    Dose
    oral cholecalciferol once weekly, 50,000 IU for the first 12 weeks then 20,000 IU for the last 12 weeks
    Population
    Haemodialysis patients with hypovitaminosis D (25(OH)D <30 ng/mL) and iPTH <300 pg/mL, not receiving vitamin D therapy; single-group before-and-after comparison with baseline; IL-6 at 6 months

    Impact of cholecalciferol treatment on biomarkers of inflammation and myocardial structure in hemodialysis patients without hyperparathyroidism.2012PMID:2190820310.1053/j.jrn.2011.07.001Permalink

To cite this finding: https://catalystproject.ai/e/01M5RTE5196ACMBR9KYRZK0DEP

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