α-tocopherol/Finding
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No detected effect on sperm concentration
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“Pooled analysis of two randomized trials showed no significant additional benefit of vitamin E versus control for sperm concentration (SMD 0.09, 95% CI-0.59 to 0.76; p = 0.80) or sperm motility (SMD 0.15, 95% CI-0.19 to 0.49; p = 0.39).”
Quoted verbatim from Effect of adjuvant vitamin E supplementation on sperm parameters after varicocelectomy: a systematic review and meta-analysis.. - Study
- meta-analysis
- Population
- Men after varicocelectomy; pooled analysis of two randomised trials of adjuvant vitamin E versus control
Effect 0.09 standardised mean difference, 95% CI -0.59 to 0.76
Effect of adjuvant vitamin E supplementation on sperm parameters after varicocelectomy: a systematic review and meta-analysis.2026PMID:42165159Permalink
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To cite this finding: https://catalystproject.ai/e/01M5NENKEZ358KA3JG3T216Q4X