strontium(2+)/Finding
One finding, on its own
A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Decreases vertebral fracture incidence
LimitedEvidence strength: limited. Human evidence with several recorded weaknesses, or a design that tops out at limited.Findingreplicated ×2“The cumulative incidence of new vertebral fractures in the 10-year population in years 6 to 10 was significantly lower than that observed over 5 years in the FRAX®-matched placebo population (20.6 ± 3.0% versus 28.2 ± 2.4%, respectively; relative reduction in risk [RRR] 35%, P = 0.016).”
Quoted verbatim from Maintenance of antifracture efficacy over 10 years with strontium ranelate in postmenopausal osteoporosis.. - Study
- cohort
- Dose
- strontium ranelate 2 g/day
- Population
- Postmenopausal women with osteoporosis who took strontium ranelate for up to 10 years in the open-label extension of SOTI and TROPOS (the 10-year population, completers only), compared in years 6 to 10 with a FRAX-matched placebo group drawn from the TROPOS placebo arm over years 0 to 5; calcium and vitamin D given
Maintenance of antifracture efficacy over 10 years with strontium ranelate in postmenopausal osteoporosis.2012PMID:22124575Permalink
Keep reading
- Everything the graph holds on strontium(2+)
- Every compound studied against Vertebral fracture incidence
- How to read the evidence strength and the marks
To cite this finding: https://catalystproject.ai/e/01M5N0YJXPM4JC6931VG6MMG8J