α-tocopherol/Finding
One finding, on its own
A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
No detected effect on prostate cancer incidence
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull resultreplicated ×3“In comparison with placebo, vitamin E supplementation had no effect on the incidence of prostate cancer (HR: 0.99; 95% CI: 0.89, 1.10) or total cancers (HR: 1.02; 95% CI: 0.95, 1.10).”
Quoted verbatim from Vitamin E and C supplementation and risk of cancer in men: posttrial follow-up in the Physicians' Health Study II randomized trial.. - Study
- RCT
- Participants
- 14,641
- Dose
- 400 IU of vitamin E every other day
- Population
- 14,641 US male physicians aged 50 or older in the Physicians' Health Study II, 2x2 factorial with vitamin C given across both vitamin E arms; trial plus posttrial observational follow-up
Effect 0.99 hazard ratio, 95% CI 0.89 to 1.1
Vitamin E and C supplementation and risk of cancer in men: posttrial follow-up in the Physicians' Health Study II randomized trial.2014PMID:25008853Permalink
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- Everything the graph holds on α-tocopherol
- Every compound studied against Prostate cancer incidence
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To cite this finding: https://catalystproject.ai/e/01M5MVGFEZN6MQHZE7TDTYV03Z